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High quality Artesunate in stock for antimalarial in stock

Artesunate is an effective antimalarial drug that treats malaria caused by Plasmodium falciparum. It kills parasites to prevent infection and rapidly relieves symptoms associated with malaria, such as fever, headache, chills, muscle pain, and anemia. Artesunate also demonstrates high safety in clinical applications.

    Function

    Artesunate is a highly effective antimalarial medication that rapidly kills Plasmodium falciparum parasites, including chloroquine-resistant strains. It is used to treat malaria infections, alleviating symptoms such as fever, headache, and chills, and helping to prevent the progression of the disease. Artesunate has been shown to be particularly effective in life-threatening cases of malaria.

    Certificate of Analysis

    Items

    Requirements

    Results

    Description

     

     

    Appearance:

    White needle crystal, odorless, taste bitter

    Conforms

    Solubility

    Freely soluble in chloroform; soluble in acetone, sparingly soluble in methanol or ethanol; practically insoluble in water

    Conforms

    Melting point

    145150, with decomposition

    146.3~146.8

    Identification

     

     

    1. Color Reaction

    bluish purple color is produced

    Conforms

    1. Color Reaction

    red color is produced which changes gradually to brown on standing

    Conforms

    1. Optical rotation

    Should show dextral optical properties

    Conforms

    1. IR

    Infrared absorption spectrum of test and standard(or infrared reference spectra No. 220) are concordant

    Conforms

    Test

     

     

    1) Related substance

    (TLC)

    Single clear spot should be obtained with solution (2). Any spot obtained with reference solution, other than the principal spot, not more than one is obtained, and is not more intense than the principal spot obtained with solution (1) (2.0%).

    Conforms

    2) Loss on drying

    ≤ 0.5%

    0.29%

    3) Residual on Ignition

    ≤ 0.1%

    0.07%

    4) Heavy metal (TLC)

    ≤ 10ppm

    Conforms

    Assay (on dried basis)

    98.0% 102.0 (HPLC)

    99.3%

    Conclusion: The product conforms to Ch.P.2010

    Application

    Artesunate is primarily used in the treatment of malaria infections caused by the Plasmodium falciparum parasite. Its efficacy against chloroquine-resistant strains makes it a valuable treatment option, particularly in areas where malaria resistance to other drugs is prevalent. Artesunate is administered to patients with malaria to rapidly kill the parasites, relieving symptoms such as fever, headache, chills, and muscle pain. In severe cases of malaria, artesunate can be administered intravenously to achieve faster and more effective results. Its applications extend to both adults and children, with appropriate dosage adjustments based on age and weight.
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