Ireme ryiza Artesunate mububiko bwa antimalarial mububiko

Izina ryibicuruzwa Artesunate
Kugaragara Ifu ya kirisiti yera
Ibisobanuro 99%
Icyemezo Halal, Kosher, ISO 22000, COA

Baza Ingero z'ubuntu

ibicuruzwa birambuye

Artesunate ni imiti igabanya ubukana ivura malariya iterwa na Plasmodium falciparum. Yica parasite kugirango irinde kwandura kandi igabanya vuba ibimenyetso bifitanye isano na malariya, nk'umuriro, kubabara umutwe, gukonja, kubabara imitsi, no kubura amaraso. Artesunate irerekana kandi umutekano mwinshi mubikorwa byubuvuzi.

Imikorere

Artesunate ni imiti igabanya ubukana bwa virusi yica vuba parasite ya Plasmodium falciparum, harimo na chloroquine. Ikoreshwa mu kuvura indwara ya malariya, kugabanya ibimenyetso nk'umuriro, kubabara umutwe, no gukonja, no gufasha kwirinda indwara. Artesunate yagaragaye ko ifite akamaro kanini mubibazo byangiza ubuzima bwa malariya.

Icyemezo cy'isesengura

Ibintu	Ibisabwa	Ibisubizo
D.ibisobanuro
Kugaragara:	Urushinge rwera rwera, rutagira impumuro nziza, uburyohe bukaze	C.imikorere
Gukemura	F.gushonga cyane muri chloroform; gushonga muri acetone, gushonga gake muri methanol cyangwa Ethanol; muburyo budashobora gushonga mumazi	Guhuza
Ingingo yo gushonga	145～150℃,hamwe nakubora	146.3~ 146.8℃
Kumenyekanisha
Ibara	A.ibara ry'ubururu bwijimye ryakozwe	C.imikorere
Ibara	A.ibara ritukura rikorwa rihinduka buhoro buhoro rihinduka igihagararo	C.imikorere
Guhinduranya neza	Ugomba kwerekana imiterere ya optique	Guhuza
NA	I.nfrared absorption specran yikizamini nibisanzwe(cyangwainfrared reference spectra No 220) birahuye	Guhuza
Ikizamini
1)R.ibintu bishimishije (TLC)	S.Ingle isobanutse neza igomba kuboneka hamwe nigisubizo (2).Ikibanza cyose cyabonetse hamweIndanganturoigisubizo, usibye umwanya wingenzi,ntibirenze kimwe cyabonetse, kandiisntibirenzeumwanya nyamukurubyabonetse hamwe nigisubizo(1)(2.0%).	C.imikorere
2) Gutakaza kumisha	≤ 0.5%	0.29%
3) IbisigayekuIgnition	≤ 0.1%	0.07%
4) Icyuma kiremereye(TLC)	≤ 10ppm	C.imikorere
Suzuma (kuri driedshingiro)	98.0%～102.0％ (HPLC)	99.3%
Umwanzuro: Ibicuruzwa bihuyeCh.P.2010

Gusaba

Artesunate ikoreshwa cyane cyane mukuvura indwara ya malariya iterwa na parasite ya Plasmodium falciparum. Ingaruka zayo zirwanya chloroquine irwanya imiti ituma iba uburyo bwiza bwo kuvura, cyane cyane aho usanga kurwanya malariya ku bindi biyobyabwenge. Artesunate ihabwa abarwayi barwaye malariya kugirango yice vuba parasite, igabanya ibimenyetso nkumuriro, kubabara umutwe, gukonja, no kubabara imitsi. Mugihe gikomeye cya malariya, artesunate irashobora gutangwa mumitsi kugirango igere kubisubizo byihuse kandi byiza. Porogaramu zayo zigera kubantu bakuru ndetse nabana, hamwe noguhindura dosiye ukurikije imyaka nuburemere.